Janet R. Casey, Michael E. Azithromycin has become a frequent choice for the treatment of group A streptococcal GAS tonsillopharyngitis. In this study, our objective was to determine the optimal dose of azithromycin for treatment of GAS tonsillopharyngitis in children and adults by analyzing trials that used different dose regimens. We performed a meta-analysis of randomized, controlled trials that involved bacteriological confirmation of GAS tonsillopharyngitis, random assignment to receive either azithromycin or a day comparator antibiotic, and assessment of bacteriological eradication by throat culture after therapy.
Are you taking the right kind of antibiotic? Half the time we're not, study says
Z pack for cold: Is it safe, and does it work?
For full functionality, it is necessary to enable JavaScript. Here are instructions how to enable JavaScript in your web browser. Healthline Media, Inc. Any data you provide will be primarily stored and processed in the United States, pursuant to the laws of the United States, which may provide lesser privacy protections than European Economic Area countries. Learn more in our Privacy Policy. We use cookies and similar technologies to improve your browsing experience, personalize content and offers, show targeted ads, analyze traffic, and better understand you.
In this study, our objective was to determine the optimal dose of azithromycin for treatment of GAS tonsillopharyngitis in children and adults by analyzing trials that used different dose regimens. METHODS: We performed a meta-analysis of randomized, controlled trials that involved bacteriological confirmation of GAS tonsillopharyngitis, random assignment to receive either azithromycin or a day comparator antibiotic, and assessment of bacteriological eradication by throat culture after therapy. The primary outcomes of interest were bacteriological and clinical cure rates. One trial used day course of 2 different comparator antibiotics, and 2 trials compared 2 dose regimens of azithromycin with a day course of comparator antibiotic; all other trials compared 1 dose regimen of azithromycin with a single day course of comparator antibiotic. In adults, no studies compared dosages by weight.
Strep throat is an infection of your throat and tonsils , the two small tissue masses in the back of your throat. The infection can cause symptoms such as sore throat and swollen glands. It can also cause fever , loss of appetite, and white spots on your tonsils.