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Current Neurology and Neuroscience Reports. September , Cite as. Postural tachycardia syndrome POTS is a form of chronic orthostatic intolerance for which the hallmark physiological trait is an excessive increase in heart rate with assumption of upright posture. The heart rate abnormality and orthostatic symptoms should not be caused by medications that impair autonomic regulation or by debilitating disorders that can cause tachycardia. Not only may patients be affected by more than one of these pathophysiologies but also the phenotype of POTS has similarities to a number of other disorders, e.
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Postural Tachycardia Syndrome: Beyond Orthostatic Intolerance

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Postural Tachycardia Syndrome: Beyond Orthostatic Intolerance | SpringerLink

Pearl K. Orthostatic hypotension OH leads to a significant number of hospitalizations each year, and is associated with significant morbidity and mortality among affected individuals. Given the increased risk for cardiovascular events and falls; it is important to identify the underlying etiology of OH and to choose appropriate therapeutic agents. Orthostatic hypotension can be non-neurogenic or neurogenic arising from a central or peripheral lesion. The initial evaluation includes orthostatic vital signs, complete history and a physical. Patients should also be evaluated for concomitant symptoms of post-prandial hypotension and supine hypertension.
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Orthostatic hypotension: managing a difficult problem

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Patient OT is a 26 year old Caucasian woman who works in the music industry. In addition to rapid palpitations, she complained of lightheadedness and presyncope on standing, intermittent stabbing chest pains typically on standing , mental clouding with an inability to concentrate, severe fatigue and exercise intolerance. She was diagnosed with postural tachycardia syndrome POTS.
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